Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse

Cell-derived exosomes have been demonstrated to be efficient carriers of small RNAs to neighbouring or distant cells, highlighting the preponderance of exosomes as carriers for gene therapy over other artificial delivery tools. In the present study, we employed modified exosomes expressing the neuro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Yuchen, Li, Dameng, Liu, Zhengya, Zhou, Yu, Chu, Danping, Li, Xihan, Jiang, Xiaohong, Hou, Dongxia, Chen, Xi, Chen, Yuda, Yang, Zhanzhao, Jin, Ling, Jiang, Waner, Tian, Chenfei, Zhou, Geyu, Zen, Ke, Zhang, Junfeng, Zhang, Yujing, Li, Jing, Zhang, Chen-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668387/
https://ncbi.nlm.nih.gov/pubmed/26633001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17543
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