Pharmacokinetic Comparability of a Biosimilar Trastuzumab Anticipated from Its Physicochemical and Biological Characterization

Comparability between a biosimilar and its reference product requires the evaluation of critical quality attributes that may impact on its pharmacological response. Herein we present a physicochemical characterization of a biosimilar trastuzumab focused on the attributes related to the pharmacokinet...

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Publicado en:Biomed Res Int
Autores principales: Miranda-Hernández, Mariana P., López-Morales, Carlos A., Piña-Lara, Nelly, Perdomo-Abúndez, Francisco C., Pérez, Néstor O., Revilla-Beltri, Jorge, Molina-Pérez, Aarón, Estrada-Marín, Larisa, Flores-Ortiz, Luis F., Ruiz-Argüelles, Alejandro, Medina-Rivero, Emilio
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668334/
https://ncbi.nlm.nih.gov/pubmed/26682224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/874916
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