Effects of Bevacizumab on Bcl-2 Expression and Apoptosis in Retinal Pigment Epithelial Cells under Oxidative Stress

PURPOSE: To evaluate the effects of bevacizumab on expression of B-cell leukemia/lymphoma (Bcl)-2 and apoptosis in retinal pigment epithelial (RPE) cells under oxidative stress conditions. METHODS: RPE cells were treated with H(2)O(2) (0, 100, 200, 300, and 400 µM) and bevacizumab at or above the do...

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Publicat a:Korean J Ophthalmol
Autors principals: Kim, Sukjin, Kim, Young Jun, Kim, Na Rae, Chin, Hee Seung
Format: Artigo
Idioma:Inglês
Publicat: The Korean Ophthalmological Society 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668259/
https://ncbi.nlm.nih.gov/pubmed/26635460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3341/kjo.2015.29.6.424
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