Donor Hepatic Steatosis Induce Exacerbated Ischemia-Reperfusion Injury through Activation of Innate Immune Response Molecular Pathways

BACKGROUND: Severe liver steatosis is a known risk factor for increased ischemia-reperfusion injury (IRI) and poor outcomes post liver transplantation (LT). This study aimed to identify steatosis-related molecular mechanisms associated with IRI exacerbation post-LT. METHODS: Paired graft biopsies (n...

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Gepubliceerd in:Transplantation
Hoofdauteurs: Gehrau, Ricardo C., Mas, Valeria R., Dumur, Catherine I., Suh, Jihee L., Sharma, Ashish K., Cathro, Helen P., Maluf, Daniel G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668234/
https://ncbi.nlm.nih.gov/pubmed/26285018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000000857
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