Ex vivo Perfusion with Adenosine A2A Receptor Agonist Enhances Rehabilitation of Murine Donor Lungs after Circulatory Death

BACKGROUND: Ex vivo lung perfusion (EVLP) enables assessment and rehabilitation of marginal donor lungs prior to transplantation. We previously demonstrated that adenosine A2A receptor (A(2A)R) agonism attenuates lung ischemia-reperfusion injury. The current study utilizes a novel murine EVLP model...

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Published in:Transplantation
Main Authors: Stone, Mathew L., Sharma, Ashish K., Mas, Valeria. R., Gehrau, Ricardo C., Mulloy, Daniel P., Zhao, Yunge, Lau, Christine L., Kron, Irving L., Laubach, Victor E.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668207/
https://ncbi.nlm.nih.gov/pubmed/26262504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000000830
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