Utilizing CMP-Sialic Acid Analogs to Unravel Neisseria gonorrhoeae Lipooligosaccharide-Mediated Complement Resistance and Design Novel Therapeutics

Neisseria gonorrhoeae deploys a novel immune evasion strategy wherein the lacto-N-neotetraose (LNnT) structure of lipooligosaccharide (LOS) is capped by the bacterial sialyltransferase, using host cytidine-5’-monophosphate (CMP)-activated forms of the nine-carbon nonulosonate (NulO) sugar N-acetyl-n...

詳細記述

保存先:
書誌詳細
出版年:PLoS Pathog
主要な著者: Gulati, Sunita, Schoenhofen, Ian C., Whitfield, Dennis M., Cox, Andrew D., Li, Jianjun, St. Michael, Frank, Vinogradov, Evgeny V., Stupak, Jacek, Zheng, Bo, Ohnishi, Makoto, Unemo, Magnus, Lewis, Lisa A., Taylor, Rachel E., Landig, Corinna S., Diaz, Sandra, Reed, George W., Varki, Ajit, Rice, Peter A., Ram, Sanjay
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668040/
https://ncbi.nlm.nih.gov/pubmed/26630657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005290
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料