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Haptotaxis is cell type specific and limited by substrate adhesiveness

Motile cells navigate through tissue by relying on tactile cues from gradients provided by extracellular matrix (ECM) such as ligand density or stiffness. Mesenchymal stem cells (MSCs) and fibroblasts encounter adhesive or ‘haptotactic’ gradients at the interface between healthy and fibrotic tissue...

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Détails bibliographiques
Publié dans:Cell Mol Bioeng
Auteurs principaux: Wen, Jessica H., Choi, Onkiu, Taylor-Weiner, Hermes, Fuhrmann, Alexander, Karpiak, Jerome V., Almutairi, Adah, Engler, Adam J.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667988/
https://ncbi.nlm.nih.gov/pubmed/26640598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-015-0398-3
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