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RANKL-RANK signaling regulates expression of Xenotropic Polytropic Virus Receptor (XPR1) in osteoclasts

Formation of multinucleated bone-resorbing osteoclasts results from activation of the Receptor activated NF-κB ligand (RANKL)-receptor activated NF-κB (RANK) signaling pathway in primary bone marrow macrophages and a macrophage cell line (RAW 264.7). Osteoclasts, through bone remodeling, are key par...

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Bibliografiske detaljer
Udgivet i:Biochem Biophys Res Commun
Main Authors: Sharma, Parul, Patntirapong, Somying, Hann, Steven, Hauschka, Peter V.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667747/
https://ncbi.nlm.nih.gov/pubmed/20633538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.07.022
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