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Comparison of TRPA1- versus TRPV1- mediated Cough in Guinea Pigs

TRPA1 receptor is activated by endogenous inflammatory mediators and exogenous pollutant molecules relevant to respiratory diseases. Previous studies have implicated TRPA1 as a drug target for antitussive therapy. Here we evaluated the relative efficacy of TRPA1 activation to evoke cough. In conscio...

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Détails bibliographiques
Publié dans:Eur J Pharmacol
Auteurs principaux: Brozmanova, Mariana, Mazurova, Lenka, Ru, Fei, Tatar, Milos, Kollarik, Marian
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667741/
https://ncbi.nlm.nih.gov/pubmed/22683866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.05.048
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