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Comparison of TRPA1- versus TRPV1- mediated Cough in Guinea Pigs
TRPA1 receptor is activated by endogenous inflammatory mediators and exogenous pollutant molecules relevant to respiratory diseases. Previous studies have implicated TRPA1 as a drug target for antitussive therapy. Here we evaluated the relative efficacy of TRPA1 activation to evoke cough. In conscio...
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| Publié dans: | Eur J Pharmacol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4667741/ https://ncbi.nlm.nih.gov/pubmed/22683866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.05.048 |
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