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Glutathione Reaction Products with a Chemical Allergen, Methylene-diphenyl Diisocyanate, Stimulate Alternative Macrophage Activation and Eosinophilic Airway Inflammation

Isocyanates have been a leading chemical cause of occupational asthma since their utility for generating polyurethane was first recognized over 60 years ago, yet the mechanisms of isocyanate asthma pathogenesis remain unclear. The present study provides in vivo evidence that a GSH mediated pathway u...

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Bibliografiska uppgifter
I publikationen:Chem Res Toxicol
Huvudupphovsmän: Wisnewski, Adam V., Liu, Jian, Colangelo, Christopher M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667722/
https://ncbi.nlm.nih.gov/pubmed/25635619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx5005002
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