Super-resolution imaging of nuclear import of adeno-associated virus in live cells

Adeno-associated virus (AAV) has been developed as a promising human gene therapy vector. Particularly, recombinant AAV vector (rAAV) achieves its transduction of host cells by crossing at least three physiological barriers including plasma membrane, endosomal membrane, and nuclear envelope (NE). So...

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Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Kelich, Joseph M, Ma, Jiong, Dong, Biao, Wang, Qizhao, Chin, Mario, Magura, Connor M, Xiao, Weidong, Yang, Weidong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667716/
https://ncbi.nlm.nih.gov/pubmed/26665132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.47
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