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Insulin receptor substrate 1 mediates insulin and insulin-like growth factor I-stimulated maturation of Xenopus oocytes.
Insulin and insulin-like growth factor I (IGF-I) initiate cellular functions by activating their homologous tyrosine kinase receptors. In most mammalian cell types, this results in rapid tyrosine phosphorylation of a high-molecular-weight substrate termed insulin receptor substrate 1 (IRS-1). Previo...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
1993
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC46677/ https://ncbi.nlm.nih.gov/pubmed/7685118 |
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