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Insulin receptor substrate 1 mediates insulin and insulin-like growth factor I-stimulated maturation of Xenopus oocytes.

Insulin and insulin-like growth factor I (IGF-I) initiate cellular functions by activating their homologous tyrosine kinase receptors. In most mammalian cell types, this results in rapid tyrosine phosphorylation of a high-molecular-weight substrate termed insulin receptor substrate 1 (IRS-1). Previo...

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Bibliographic Details
Main Authors: Chuang, L M, Myers, M G, Seidner, G A, Birnbaum, M J, White, M F, Kahn, C R
Format: Artigo
Language:Inglês
Published: 1993
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC46677/
https://ncbi.nlm.nih.gov/pubmed/7685118
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