Engineering and expression of a human rotavirus candidate vaccine in Nicotiana benthamiana

BACKGROUND: Human rotaviruses are the main cause of severe gastroenteritis in children and are responsible for over 500 000 deaths annually. There are two live rotavirus vaccines currently available, one based on human rotavirus serotype G1P[8], and the other a G1-G4 P[8] pentavalent vaccine. Howeve...

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Enregistré dans:
Détails bibliographiques
Publié dans:Virol J
Auteurs principaux: Pêra, Francisco F. P. G., Mutepfa, David L. R., Khan, Ayesha M., Els, Johann H., Mbewana, Sandiswa, van Dijk, Alberdina A. A., Rybicki, Edward P., Hitzeroth, Inga I.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667453/
https://ncbi.nlm.nih.gov/pubmed/26626122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0436-8
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