Early-Stage White Matter Lesions Detected by Multispectral MRI Segmentation Predict Progressive Cognitive Decline

White matter lesions (WML) are the main brain imaging surrogate of cerebral small-vessel disease. A new MRI tissue segmentation method, based on a discriminative clustering approach without explicit model-based added prior, detects partial WML volumes, likely representing very early-stage changes in...

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Bibliographische Detailangaben
Veröffentlicht in:Front Neurosci
Hauptverfasser: Jokinen, Hanna, Gonçalves, Nicolau, Vigário, Ricardo, Lipsanen, Jari, Fazekas, Franz, Schmidt, Reinhold, Barkhof, Frederik, Madureira, Sofia, Verdelho, Ana, Inzitari, Domenico, Pantoni, Leonardo, Erkinjuntti, Timo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667087/
https://ncbi.nlm.nih.gov/pubmed/26696814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00455
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