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Rad and Rem are non‐canonical G‐proteins with respect to the regulatory role of guanine nucleotide binding in Ca(V)1.2 channel regulation

KEY POINTS: RGK (Rad, Rem, Rem2, Gem/Kir) proteins are small monomeric G‐proteins implicated in various cellular functions and disease states. All RGK proteins potently inhibit voltage‐gated calcium (Ca(V)) channels. It is unclear whether RGK proteins are regulated by guanine nucleotide binding in a...

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Foilsithe in:J Physiol
Main Authors: Chang, Donald D., Colecraft, Henry M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666999/
https://ncbi.nlm.nih.gov/pubmed/26426338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270889
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