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Rad and Rem are non‐canonical G‐proteins with respect to the regulatory role of guanine nucleotide binding in Ca(V)1.2 channel regulation

KEY POINTS: RGK (Rad, Rem, Rem2, Gem/Kir) proteins are small monomeric G‐proteins implicated in various cellular functions and disease states. All RGK proteins potently inhibit voltage‐gated calcium (Ca(V)) channels. It is unclear whether RGK proteins are regulated by guanine nucleotide binding in a...

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Détails bibliographiques
Publié dans:J Physiol
Auteurs principaux: Chang, Donald D., Colecraft, Henry M.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666999/
https://ncbi.nlm.nih.gov/pubmed/26426338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270889
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