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Rad and Rem are non‐canonical G‐proteins with respect to the regulatory role of guanine nucleotide binding in Ca(V)1.2 channel regulation

KEY POINTS: RGK (Rad, Rem, Rem2, Gem/Kir) proteins are small monomeric G‐proteins implicated in various cellular functions and disease states. All RGK proteins potently inhibit voltage‐gated calcium (Ca(V)) channels. It is unclear whether RGK proteins are regulated by guanine nucleotide binding in a...

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Vydáno v:J Physiol
Hlavní autoři: Chang, Donald D., Colecraft, Henry M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666999/
https://ncbi.nlm.nih.gov/pubmed/26426338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270889
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