Sodium nitrate alleviates functional muscle ischaemia in patients with Becker muscular dystrophy

KEY POINTS: Dystrophin deficiency disrupts sarcolemmal targeting of neuronal nitric oxide synathase, resulting in functional muscle ischaemia. Chronic treatment of dystrophic mice with an inorganic nitric oxide (NO) donor alleviates this ischaemia and improves many features of the dystrophic phenoty...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Nelson, Michael D., Rosenberry, Ryan, Barresi, Rita, Tsimerinov, Evgeny I., Rader, Florian, Tang, Xiu, Mason, O'Neil, Schwartz, Avery, Stabler, Thomas, Shidban, Sarah, Mobaligh, Neigena, Hogan, Shomari, Elashoff, Robert, Allen, Jason D., Victor, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Integrative
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666991/
https://ncbi.nlm.nih.gov/pubmed/26437761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271252
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