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Shear stress induces a longitudinal Ca(2+) wave via autocrine activation of P2Y(1) purinergic signalling in rat atrial myocytes

KEY POINTS: Cardiac myocytes are subjected to fluid shear stress during the cardiac cycle and haemodynamic disturbance. A longitudinally propagating, regenerative Ca(2+) wave is initiated in atrial myocytes under shear stress. Here we determine the cellular mechanism for this shear‐induced Ca(2+) wa...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Kim, Joon‐Chul, Woo, Sun‐Hee
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666989/
https://ncbi.nlm.nih.gov/pubmed/26377030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271016
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