An increased population of regulatory T cells improves the pathophysiology of placental ischemia in a rat model of preeclampsia

The reduced uterine perfusion pressure (RUPP) rat model of preeclampsia exhibits much of the pathology characterizing this disease, such as hypertension, inflammation, suppressed regulatory T cells (T(Reg)s), reactive oxygen species (ROS), and autoantibodies to the ANG II type I receptor (AT(1)-AA)...

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Veröffentlicht in:Am J Physiol Regul Integr Comp Physiol
Hauptverfasser: Cornelius, Denise C., Amaral, Lorena M., Harmon, Ashlyn, Wallace, Kedra, Thomas, Alexia J., Campbell, Nathan, Scott, Jeremy, Herse, Florian, Haase, Nadine, Moseley, Janae, Wallukat, Gerd, Dechend, Ralf, LaMarca, Babbette
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
Schlagworte:
Fluid and Electrolyte Homeostasis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666948/
https://ncbi.nlm.nih.gov/pubmed/26290102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00154.2015
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