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Role played by NaV 1.7 channels on thin-fiber muscle afferents in transmitting the exercise pressor reflex

Voltage-gated sodium channels (NaV) 1.7 are highly expressed on the axons of somatic afferent neurons and are thought to play an important role in the signaling of inflammatory pain. NaV 1.7 channels are classified as tetrodotoxin (TTX)-sensitive, meaning that they are blocked by TTX concentrations...

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Pubblicato in:Am J Physiol Regul Integr Comp Physiol
Autori principali: Stone, Audrey J., Copp, Steven W., Kaufman, Marc P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666938/
https://ncbi.nlm.nih.gov/pubmed/26310938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00246.2015
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