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Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents

Most antimicrobial peptides act upon target microorganisms by permeabilizing their membranes. The mode of action is often assessed by vesicle leakage experiments that use model membranes, with the assumption that biological activity arises from permeabilization of the lipid bilayer. The current work...

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Detalhes bibliográficos
Publicado no:Soft Matter
Main Authors: Hovakeemian, Sara G., Liu, Runhui, Gellman, Samuel H., Heerklotz, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666704/
https://ncbi.nlm.nih.gov/pubmed/26234884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sm01521a
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