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Intergenic Alu exonisation facilitates the evolution of tissue-specific transcript ends
The 3′ untranslated regions (3′ UTRs) of transcripts serve as important hubs for posttranscriptional gene expression regulation. Here, we find that the exonisation of intergenic Alu elements introduced new terminal exons and polyadenylation sites during human genome evolution. While Alu exonisation...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666398/ https://ncbi.nlm.nih.gov/pubmed/26400176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv956 |
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