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Thermodynamic properties of water molecules in the presence of cosolute depend on DNA structure: a study using grid inhomogeneous solvation theory

In conditions that mimic those of the living cell, where various biomolecules and other components are present, DNA strands can adopt many structures in addition to the canonical B-form duplex. Previous studies in the presence of cosolutes that induce molecular crowding showed that thermal stabiliti...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Nakano, Miki, Tateishi-Karimata, Hisae, Tanaka, Shigenori, Tama, Florence, Miyashita, Osamu, Nakano, Shu-ichi, Sugimoto, Naoki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666364/
https://ncbi.nlm.nih.gov/pubmed/26538600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1133
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