Incidence and risk factors of bleeding-related adverse events in patients with chronic lymphocytic leukemia treated with ibrutinib

Ibrutinib is associated with bleeding-related adverse events of grade ≤2 in severity, and infrequently with grade ≥3 events. To investigate the mechanisms of bleeding and identify patients at risk, we prospectively assessed platelet function and coagulation factors in our investigator-initiated tria...

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Veröffentlicht in:Haematologica
Hauptverfasser: Lipsky, Andrew H., Farooqui, Mohammed Z.H., Tian, Xin, Martyr, Sabrina, Cullinane, Ann M., Nghiem, Khanh, Sun, Clare, Valdez, Janet, Niemann, Carsten U., Herman, Sarah E. M., Saba, Nakhle, Soto, Susan, Marti, Gerald, Uzel, Gulbu, Holland, Steve M., Lozier, Jay N., Wiestner, Adrian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666333/
https://ncbi.nlm.nih.gov/pubmed/26430171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.126672
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