Incidence and risk factors of bleeding-related adverse events in patients with chronic lymphocytic leukemia treated with ibrutinib

Ibrutinib is associated with bleeding-related adverse events of grade ≤2 in severity, and infrequently with grade ≥3 events. To investigate the mechanisms of bleeding and identify patients at risk, we prospectively assessed platelet function and coagulation factors in our investigator-initiated tria...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Lipsky, Andrew H., Farooqui, Mohammed Z.H., Tian, Xin, Martyr, Sabrina, Cullinane, Ann M., Nghiem, Khanh, Sun, Clare, Valdez, Janet, Niemann, Carsten U., Herman, Sarah E. M., Saba, Nakhle, Soto, Susan, Marti, Gerald, Uzel, Gulbu, Holland, Steve M., Lozier, Jay N., Wiestner, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666333/
https://ncbi.nlm.nih.gov/pubmed/26430171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.126672
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