Design and Evaluation of the Highly Concentrated Human IgG Formulation Using Cyclodextrin Polypseudorotaxane Hydrogels

To achieve the potent therapeutic effects of human immunoglobulin G (IgG), highly concentrated formulations are required. However, the stabilization for highly concentrated human IgG is laborious work. In the present study, to investigate the potentials of polypseudorotaxane (PPRX) hydrogels consist...

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Publicado en:AAPS PharmSciTech
Autores principales: Higashi, Taishi, Tajima, Anna, Ohshita, Naoko, Hirotsu, Tatsunori, Hashim, Irhan Ibrahim Abu, Motoyama, Keiichi, Koyama, Sawako, Iibuchi, Ruriko, Mieda, Shiuhei, Handa, Kenji, Kimoto, Tomoaki, Arima, Hidetoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666269/
https://ncbi.nlm.nih.gov/pubmed/25776984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0309-x
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