Enhancement of Oral Bioavailability of Curcumin by a Novel Solid Dispersion System

The objective of this study was to improve the solubility and bioavailability of curcumin by a new curcumin dripping pills (Cur-DPs) formulation using melt mixing methods. The optimal formulation consisted of Polyethoxylated 40 hydrogenated castor oil (Cremophor RH40), Poloxamer 188, and Polyethylen...

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Bibliographic Details
Published in:AAPS PharmSciTech
Main Authors: Hu, Liandong, Shi, Yanjing, Li, Jian Heng, Gao, Na, Ji, Jing, Niu, Feng, Chen, Queting, Yang, Xiaoning, Wang, Shaocheng
Format: Artigo
Language:Inglês
Published: Springer US 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666267/
https://ncbi.nlm.nih.gov/pubmed/25804949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0254-0
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