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ADMIRE: analysis and visualization of differential methylation in genomic regions using the Infinium HumanMethylation450 Assay
BACKGROUND: DNA methylation at cytosine nucleotides constitutes epigenetic gene regulation impacting cellular development and a wide range of diseases. Cytosine bases of the DNA are converted to 5-methylcytosine by the methyltransferase enzyme, acting as a reversible regulator of gene expression. Du...
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Published in: | Epigenetics Chromatin |
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Main Authors: | , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
BioMed Central
2015
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666223/ https://ncbi.nlm.nih.gov/pubmed/26628921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-015-0045-1 |
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