Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson’s disease

INTRODUCTION: Parkinson’s disease (PD) is characterized by the accumulation of abnormal α-synuclein in selected regions of the brain following a gradient of severity with disease progression. Whether this is accompanied by globally altered protein synthesis is poorly documented. The present study wa...

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Publicado en:Acta Neuropathol Commun
Autores principales: Garcia-Esparcia, Paula, Hernández-Ortega, Karina, Koneti, Anusha, Gil, Laura, Delgado-Morales, Raul, Castaño, Ester, Carmona, Margarita, Ferrer, Isidre
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666041/
https://ncbi.nlm.nih.gov/pubmed/26621506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0257-4
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