Magnetic resonance image features identify glioblastoma phenotypic subtypes with distinct molecular pathway activities

Glioblastoma (GBM) is the most common and highly lethal primary malignant brain tumor in adults. There is a dire need for easily accessible, noninvasive biomarkers that can delineate underlying molecular activities and predict response to therapy. To this end, we sought to identify subtypes of GBM,...

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Published in:Sci Transl Med
Main Authors: Itakura, Haruka, Achrol, Achal S., Mitchell, Lex A., Loya, Joshua J., Liu, Tiffany, Westbroek, Erick M., Feroze, Abdullah H., Rodriguez, Scott, Echegaray, Sebastian, Azad, Tej D., Yeom, Kristen W., Napel, Sandy, Rubin, Daniel L., Chang, Steven D., Harsh, Griffith R., Gevaert, Olivier
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666025/
https://ncbi.nlm.nih.gov/pubmed/26333934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa7582
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