Magnetic resonance image features identify glioblastoma phenotypic subtypes with distinct molecular pathway activities

Glioblastoma (GBM) is the most common and highly lethal primary malignant brain tumor in adults. There is a dire need for easily accessible, noninvasive biomarkers that can delineate underlying molecular activities and predict response to therapy. To this end, we sought to identify subtypes of GBM,...

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Pubblicato in:Sci Transl Med
Autori principali: Itakura, Haruka, Achrol, Achal S., Mitchell, Lex A., Loya, Joshua J., Liu, Tiffany, Westbroek, Erick M., Feroze, Abdullah H., Rodriguez, Scott, Echegaray, Sebastian, Azad, Tej D., Yeom, Kristen W., Napel, Sandy, Rubin, Daniel L., Chang, Steven D., Harsh, Griffith R., Gevaert, Olivier
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666025/
https://ncbi.nlm.nih.gov/pubmed/26333934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa7582
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