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Lack of integrase inhibitors associated resistance mutations among HIV-1C isolates

BACKGROUND: Although biochemical analysis of HIV-1 integrase enzyme suggested the use of integrase inhibitors (INIs) against HIV-1C, different viral subtypes may favor different mutational pathways potentially leading to varying levels of drug resistance. Thus, the aim of this study was to search fo...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Mulu, Andargachew, Maier, Melanie, Liebert, Uwe Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665939/
https://ncbi.nlm.nih.gov/pubmed/26626277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0734-3
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