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Comparative assessment of native and heterologous 2-oxo acid decarboxylases for application in isobutanol production by Saccharomyces cerevisiae

BACKGROUND: Decarboxylation of α-ketoisovalerate to isobutyraldehyde is a key reaction in metabolic engineering of Saccharomyces cerevisiae for isobutanol production with published studies relying on overexpression of either the native ARO10 gene or of the Lactococcus lactis kivD decarboxylase gene...

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Détails bibliographiques
Publié dans:Biotechnol Biofuels
Auteurs principaux: Milne, N., van Maris, A. J. A., Pronk, J. T., Daran, J. M.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665922/
https://ncbi.nlm.nih.gov/pubmed/26628917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-015-0374-0
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