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Transcriptional activation of the IGF-II/IGF-1R axis and inhibition of IGFBP-3 by miR-155 in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is characterized by the aberrant expression of a number of genes that govern crucial signaling pathways. The insulin-like growth factor (IGF) axis is important in this context, and the precise regulation of expression of members of this axis is known to be lost in HCC....

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Détails bibliographiques
Publié dans:Oncol Lett
Auteurs principaux: EL TAYEBI, HEND M., WALY, AMR A., ASSAL, REEM A., HOSNY, KARIM A., ESMAT, GAMAL, ABDELAZIZ, AHMED I.
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665895/
https://ncbi.nlm.nih.gov/pubmed/26722313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3725
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