A collagen VI–dependent pathogenic mechanism for Hirschsprung’s disease

Hirschsprung’s disease (HSCR) is a severe congenital anomaly of the enteric nervous system (ENS) characterized by functional intestinal obstruction due to a lack of intrinsic innervation in the distal bowel. Distal innervation deficiency results from incomplete colonization of the bowel by enteric n...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Soret, Rodolphe, Mennetrey, Mathilde, Bergeron, Karl F., Dariel, Anne, Neunlist, Michel, Grunder, Franziska, Faure, Christophe, Silversides, David W., Pilon, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665793/
https://ncbi.nlm.nih.gov/pubmed/26571399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83178
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