Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets

Thrombosis is a common, life-threatening consequence of systemic infection; however, the underlying mechanisms that drive the formation of infection-associated thrombi are poorly understood. Here, using a mouse model of systemic Salmonella Typhimurium infection, we determined that inflammation in ti...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Hitchcock, Jessica R., Cook, Charlotte N., Bobat, Saeeda, Ross, Ewan A., Flores-Langarica, Adriana, Lowe, Kate L., Khan, Mahmood, Dominguez-Medina, C. Coral, Lax, Sian, Carvalho-Gaspar, Manuela, Hubscher, Stefan, Rainger, G. Ed, Cobbold, Mark, Buckley, Christopher D., Mitchell, Tim J., Mitchell, Andrea, Jones, Nick D., Van Rooijen, N., Kirchhofer, Daniel, Henderson, Ian R., Adams, David H., Watson, Steve P., Cunningham, Adam F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2015
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665792/
https://ncbi.nlm.nih.gov/pubmed/26571395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79070
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items