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Hirschsprung’s disease, Down syndrome, and missing heritability: too much collagen slows migration
Hirschsprung’s disease (HSCR) causes functional intestinal obstruction due to the absence of the enteric nervous system (ENS) in the distal bowel and is usually diagnosed shortly after birth or during childhood. While several genetic and nongenetic factors have been linked to HSCR, the underlying me...
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| Publicado no: | J Clin Invest |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4665790/ https://ncbi.nlm.nih.gov/pubmed/26571392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85003 |
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