Rabbit antithymocyte globulin–induced serum sickness disease and human kidney graft survival

BACKGROUND. Rabbit-generated antithymocyte globulins (ATGs), which target human T cells, are widely used as immunosuppressive agents during treatment of kidney allograft recipients. However, ATGs can induce immune complex diseases, including serum sickness disease (SSD). Rabbit and human IgGs have v...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Couvrat-Desvergnes, Grégoire, Salama, Apolline, Le Berre, Ludmilla, Evanno, Gwénaëlle, Viklicky, Ondrej, Hruba, Petra, Vesely, Pavel, Guerif, Pierrick, Dejoie, Thomas, Rousse, Juliette, Nicot, Arnaud, Bach, Jean-Marie, Ang, Evelyn, Foucher, Yohann, Brouard, Sophie, Castagnet, Stéphanie, Giral, Magali, Harb, Jean, Perreault, Hélène, Charreau, Béatrice, Lorent, Marine, Soulillou, Jean-Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2015
Schlagworte:
Clinical Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665787/
https://ncbi.nlm.nih.gov/pubmed/26551683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82267
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