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SDF1 induction by acidosis from principal cells regulates intercalated cell subtype distribution

The nephron cortical collecting duct (CCD) is composed of principal cells, which mediate Na, K, and water transport, and intercalated cells (ICs), which are specialized for acid-base transport. There are two canonical IC forms: acid-secreting α-ICs and HCO(3)-secreting β-ICs. Chronic acidosis increa...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Schwartz, George J., Gao, XiaoBo, Tsuruoka, Shuichi, Purkerson, Jeffrey M., Peng, Hu, D’Agati, Vivette, Picard, Nicolas, Eladari, Dominique, Al-Awqati, Qais
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665773/
https://ncbi.nlm.nih.gov/pubmed/26517693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80225
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