Endothelial-to-mesenchymal transition drives atherosclerosis progression

The molecular mechanisms responsible for the development and progression of atherosclerotic lesions have not been fully established. Here, we investigated the role played by endothelial-to-mesenchymal transition (EndMT) and its key regulator FGF receptor 1 (FGFR1) in atherosclerosis. In cultured hum...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Chen, Pei-Yu, Qin, Lingfeng, Baeyens, Nicolas, Li, Guangxin, Afolabi, Titilayo, Budatha, Madhusudhan, Tellides, George, Schwartz, Martin A., Simons, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665771/
https://ncbi.nlm.nih.gov/pubmed/26517696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82719
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