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Inhibition of autophagy enhances cisplatin-induced apoptosis in the MG63 human osteosarcoma cell line

Autophagy is a significant catabolic process that allows the renewal of intracellular organelles, through which cells are able to maintain homeostasis. In addition, autophagy may be associated with the carcinogenesis of osteosarcoma (OS). Cisplatin (CDDP) is an alkylating agent that is commonly used...

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Publicat a:Oncol Lett
Autors principals: ZHANG, ZHICAI, SHAO, ZENGWU, XIONG, LIMING, YANG, SHUHUA
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665755/
https://ncbi.nlm.nih.gov/pubmed/26722268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3692
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