Angiotensin II type-1 receptor blockers enhance the effects of bevacizumab-based chemotherapy in metastatic colorectal cancer patients

The local renin-angiotensin system promotes angiogenesis and vascular proliferation via expression of vascular endothelial growth factor or epidermal growth factor receptor. We hypothesized that angiotensin II type-1 receptor blockers (ARBs) in combination with bevacizumab (Bev) may improve clinical...

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Publicado en:Mol Clin Oncol
Autores principales: OSUMI, HIROKI, MATSUSAKA, SATOSHI, WAKATSUKI, TAKERU, SUENAGA, MITSUKUNI, SHINOZAKI, EIIJ, MIZUNUMA, NOBUYUKI
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2015
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665652/
https://ncbi.nlm.nih.gov/pubmed/26807236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2015.630
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