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Epigenetic changes and nuclear factor-κB activation, but not microRNA-224, downregulate Raf-1 kinase inhibitor protein in triple-negative breast cancer SUM 159 cells

Raf-1 kinase inhibitor protein (RKIP) is a tumor suppressor and metastasis inhibitor, which enhances drug-induced apoptosis of cancer cells. Downregulation of RKIP may be significant in the biology of highly aggressive and drug-resistant tumors, for example triple-negative breast cancers (TNBCs). Po...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: LABBOZZETTA, MANUELA, POMA, PAOLA, VIVONA, NICOLETTA, GULINO, ALESSANDRO, D'ALESSANDRO, NATALE, NOTARBARTOLO, MONICA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665334/
https://ncbi.nlm.nih.gov/pubmed/26788213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3787
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