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Loss of autophagy-related protein Beclin 1 may define poor prognosis in ovarian clear cell carcinomas

The aim of the present study was to clarify the role of autophagy in cisplatin (CDDP) sensitivity in OCCCs and the role of Beclin 1 in OCCC progression. Autophagy was measured using: i) western blot analysis of LC3 and p62 and ii) microscopic observation of GFP-LC3 puncta. Autophagy was suppressed u...

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Dades bibliogràfiques
Publicat a:Int J Oncol
Autors principals: KATAGIRI, HIROSHI, NAKAYAMA, KENTARO, RAZIA, SULTANA, NAKAMURA, KOHEI, SATO, EMI, ISHIBASHI, TOMOKA, ISHIKAWA, MASAKO, IIDA, KOUJI, ISHIKAWA, NORIYOSHI, OTSUKI, YOSHIRO, NAKAYAMA, SATORU, KYO, SATORU
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665333/
https://ncbi.nlm.nih.gov/pubmed/26458502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3191
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