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Increased activity of CHK enhances the radioresistance of MCF-7 breast cancer stem cells

The resistance of breast cancer to radiotherapy remains a major obstacle to successful cancer management. Radiotherapy may result in DNA damage and activate breast cancer stem cells. DNA damage may lead to activation of the checkpoint kinase (CHK) signaling pathway, of which debromohymenialdisine (D...

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Dades bibliogràfiques
Publicat a:Oncol Lett
Autors principals: YANG, ZHI-XUE, SUN, YI-HUI, HE, JIAN-GANG, CAO, HUA, JIANG, GUO-QIN
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665200/
https://ncbi.nlm.nih.gov/pubmed/26788148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3777
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