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Delivery of miR-34a by chitosan/PLGA nanoplexes for the anticancer treatment of multiple myeloma

The encapsulation of miR-34a into chitosan/PLGA nanoparticles in order to obtain nanoplexes useful for the modulation of the biopharmaceutical features of the active compound was studied. The nanoplexes were obtained through nanoprecipitation and were characterized by a mean diameter of ~160 nm, a g...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cosco, Donato, Cilurzo, Felisa, Maiuolo, Jessica, Federico, Cinzia, Di Martino, Maria Teresa, Cristiano, Maria Chiara, Tassone, Pierfrancesco, Fresta, Massimo, Paolino, Donatella
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665167/
https://ncbi.nlm.nih.gov/pubmed/26620594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17579
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