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Modulation of the interaction between G-actin and thymosin beta 4 by the ATP/ADP ratio: possible implication in the regulation of actin dynamics.

The interaction of G-actin with thymosin beta 4 (T beta 4), the major G-actin-sequestering protein in motile and proliferating cells, has been analyzed in vitro. T beta 4 is found to have a 50-fold higher affinity for MgATP-actin than for MgADP-actin. These results imply that in resting platelets an...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Carlier, M F, Jean, C, Rieger, K J, Lenfant, M, Pantaloni, D
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC46648/
https://ncbi.nlm.nih.gov/pubmed/8506348
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