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Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes.

5-Hydroxytryptamine type 3 receptors were expressed in Xenopus oocytes from a cloned cDNA. The peak inward current evoked by 5-hydroxytryptamine (30 microM) was linearly related to the holding potential (-100 to +20 mV) and reversed near 0 mV. The inward current (at -60 mV) declined during the conti...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Yakel, J L, Lagrutta, A, Adelman, J P, North, R A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1993
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46647/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8506347/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.11.5030
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