Identification and Mechanistic Investigation of Drug–Drug Interactions Associated With Myopathy: A Translational Approach

Myopathy is a group of muscle diseases that can be induced or exacerbated by drug–drug interactions (DDIs). We sought to identify clinically important myopathic DDIs and elucidate their underlying mechanisms. Five DDIs were found to increase the risk of myopathy based on analysis of observational da...

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Bibliographic Details
Published in:Clin Pharmacol Ther
Main Authors: Han, X, Quinney, SK, Wang, Z, Zhang, P, Duke, J, Desta, Z, Elmendorf, JS, Flockhart, DA, Li, L
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664558/
https://ncbi.nlm.nih.gov/pubmed/25975815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.150
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