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Global shape mimicry of tRNA within a viral internal ribosome entry site mediates translational reading frame selection
The dicistrovirus intergenic region internal ribosome entry site (IRES) adopts a triple-pseudoknotted RNA structure and occupies the core ribosomal E, P, and A sites to directly recruit the ribosome and initiate translation at a non-AUG codon. A subset of dicistrovirus IRESs directs translation in t...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4664324/ https://ncbi.nlm.nih.gov/pubmed/26554019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512088112 |
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