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Extracellular matrix remodeling and cell phenotypic changes in dysplastic and hemodynamically altered semilunar human cardiac valves

INTRODUCTION: Congenital cardiac valve disease is common, affecting ~1% of the population, with substantial morbidity and mortality, but suboptimal treatment options. Characterization of the specific matrix and valve cell phenotypic abnormalities in these valves could lend insight into disease patho...

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Foilsithe in:Cardiovasc Pathol
Main Authors: Stephens, Elizabeth H., Shangkuan, Jennifer, Kuo, Joyce J., Carroll, Joshua L., Kearney, Debra L., Carberry, Kathleen E., Fraser, Charles D., Grande-Allen, K. Jane
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664042/
https://ncbi.nlm.nih.gov/pubmed/20817569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2010.07.004
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